Symptoms Significantly Reduced With Lip Clear® Lysine + Topical Ointment
Lip Clear Lysine+ Clinical Study From Alternative Medicine Review (V10, No.2, 6/05)
Eugene, OR: A study published in Alternative Medicine Review (6/05) shows that LIP CLEARLysine+ topical ointment healed cold sores faster than leading OTC and prescription brands costing 3 to 5 times more. Median healing time was just 4.0 days. Within three days, the formula either completely eliminated or dramatically reduced cold sore symptoms, including tingling, burning, itching, tenderness, prickling, soreness and blistering. In addition, a remarkable 40% of the participants had full cure by end of the third day.The all natural ointment, LIP CLEAR Lysine+ is available in the USA and Canada or www.lipclear.com or call 1-800-448-1448.
Cold sore sufferers using LIP CLEAR Lysine+ topical ointment healed more quickly and experienced significantly reduced symptoms, according to a study from Southern California University of Health Sciences published this week in the peer reviewed journal, Alternative Medicine Review (Volume 10, No. 2). That's good news for the 60 million people with active cold sores
"The formula reduced the duration of cold sore symptoms by 50% or more when compared to untreated cold sore data" said Betsy Singh, PhD, the University's Dean of Research. The median healing time was 4.0 days - 1/2 to 1 full day shorter than in the studies on the leading prescription and OTC brands that cost 3 to 5 times more
The study was co-authored by Jay Udani, MD, Medical Director of the Integrative Medicine Program at Northridge Hospital, Assistant Clinical Professor at the UCLA / Geffen School of Medicine and Adjunct Professor of Research at SCU.
The study, Safety and Effectiveness of an L-Lysine, Zinc, and Herbal-Based Product on the Treatment of Facial and Circumoral Herpes, also showed that within three days, LIP CLEAR either completely eliminated or dramatically reduced cold sore symptoms, including tingling, burning, itching, tenderness, prickling, soreness and blistering. In addition, a remarkable 40% of the participants were fully cured by the end of the third day. No adverse effects were reported.
The LIP CLEAR Lysine+ formula includes a proprietary blend of L-Lysine and 14 nutrients, (natural zinc oxide, Vitamins A, D and E, extracts of goldenseal, propolis, calendula, echinacea; cajeput and tea tree oil, and gum benzoin tincture, honey and lithium carbonate in a base of olive oil and yellow beeswax). For more information, visit www.lipclear.com or call 1-800-448-1448. The product is marketed as Super Lysine+ in health food stores.
According to the researchers, participants commented that the formula provided a superior experience compared to other formulas: it was invisible, could be worn under lipstick, did not burn when applied, and provided immediate relief.
This open label outcome study measured time to full cure as well as ten common symptoms. Full cure referred to the complete disappearance of the lesion, not merely crusting, which is the end point in most studies (crusting may take 2 to 7 more days to disappear). The ten factors for monitoring the sores were: tingling, itching, burning, tenderness, prickling, soreness, bump/swelling, small blister(s), oozing blister(s), and crusting. 120 subjects pre-enrolled and 30 subjects, (half male/female, aged 28 to 65) participated. All subjects were experienced cold sore sufferers and were familiar with the efficiency of other treatments.
Cold sores are small blisters that form around the mouth. They are clear and filled with fluid. Cold sores are caused by the herpes simplex virus, which lives inside nerve tissue. It is estimated that 80% of the population carry the virus and 60 million people have outbreaks once or more per year. Cold sores are also known as Herpes Simplex or HSV1 (not the same as genital herpes) and may be referred to as fever blisters. Cold sores can be triggered by sunlight, fever, illness, stress, arginine rich foods such as chocolate, food allergies, or hormonal changes. Early symptoms of an outbreak are itching, tingling, or burning. Cold sores are contagious and can be spread by kissing or sharing eating utensils, toothbrushes, towels or razors
Safety and Effectiveness of an L-Lysine, Zinc, and Herbal-Based Product on the Treatment of Facial and Circumoral Herpes
CONTEXT: L-lysine, an essential amino acid, inhibits normal replication of Herpes simplex virus (HSV), shortening the normal course and duration of the disease. This study was conducted to determine the effectiveness of a combination of L-lysine with botanicals and other nutrients in relieving the symptoms of facial and circumoral herpes.
METHODS: This small pilot study was conducted using an outcome (open-label) model. Thirty male and female participants (15 in each group) meeting the inclusion/exclusion criteria were admitted to the study. The 10 outcome measures used to monitor the sores were tingling, itching, burning, tenderness, prickling, soreness, bump/swelling, small blister(s), oozing blister(s), and crusting. The study also utilized before-and-after photographs of the lesions and a daily diary.
RESULTS: At the end of treatment, the ointment produced full resolution in 40 percent of the participants by the third day and in 87 percent by the end of the sixth day. A cold sore episode can last up to 21 days without treatment. CONCLUSIONS: Overall data indicated significant improvement in participants by the sixth day of treatment for all but two participants. There were no adverse effects reported during this study. (Altern Med Rev 2005;10(2))
Authored By: Betsy B. Singh, PhD; Jay Udani, MD; Sivarama Prasad Vinjamury, MD (Ayurveda); Claudia Der-Martirosian, PhD; Sonal Gandhi, MD; Raheleh Khorsan, MA; Dinesha Nanjegowda, PhD; and Vijay Singh, PsyD (Candidate)