- Pycnogenol Awarded Patent For Reducing PMS / Menstrual Pain
Pycnogenol Awarded Patent For Reducing PMS / Menstrual Pain
Geneva, June 20, 2002 - Horphag Research announces today that Pycnogenol® has been awarded a US patent for use of proanthocyanidins in the reduction of the pain and discomfort associated with menstruation (PMS).
Abdominal pain due to endometriosis was reduced in 80% of the patients and cramps disappeared in 77% of the women taking Pynogenol®, according to a study published in the European Bulletin of Drug Research and submitted as part of the patent application. Endometriosis is a common gynecological disorder with varied symptoms including chronic pelvic pain, dysmenorrhea and infertility.
The United States Patent and Trademark Office awarded Patent No. US 6,372,266 to Pycnogenol® for the "unexpected" finding that it exhibits "unprecedented remarkable ameliorating or therapeutic effects on patients with dysmenorrhea and endometriosis," as it was described in the application.
"This patent opens the door to allow women to choose a more natural and effective approach to alleviating the discomfort with menstruation and associated conditions," says Victor Ferrari, Chief Operating Officer, Horphag Research. "This patent further increases the value of Pycnogenol® as an addition to women's health formulas, multivitamins or as a stand alone product."
Pycnogenol® is a natural complex of water-soluble bioflavonoids. When compared against 20 other antioxidants sources, Pycnogenol® was shown to be the most powerful antioxidant among them. In addition, it increases the effect of vitamin antioxidants like C and E when they are taken together.
The antioxidants in Pycnogenol® may counteract cramps by reducing inflammatory action. Recent studies have shown a clear improvement in terms of reduction of menstrual cramps and pain in 73% of women following administration of 30 mg Pycnogenol®day for one month, in addition to those with endometriosis.
"The results of our study indicate that a Pycnogenol® treatment seems to be useful in improving the menstrual and pelvic pain in women, " Dr. Takafumi Kohama, of Keiju Medical Center and the Kanazawa University School of Medicine said. "The mode of action, by which Pycnogenol® reduces the clinical findings of endometriosis and chronic pelvic pain, is thought to be a combined action of its individual components."
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Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product is protected by one ore more of U.S. patents #4,698,360 / #5,720,956 / #6,372,266 and other international patents